Disparity in market prices for hepatitis C virus direct-acting drugs.

نویسندگان

  • Isabelle Andrieux-Meyer
  • Jennifer Cohn
  • Evaldo S Affonso de Araújo
  • Saeed S Hamid
چکیده

www.thelancet.com/lancetgh Vol 3 November 2015 e676 gross national income (figure). In high-income countries, the price per bottle of sofosbuvir ranged from $14 000 (Spain) to $20 590 (Switzerland). Prices for daclatasvir ranged from $1128 (South Korea) to $14 899 (Germany); those of simeprevir from $9166 (Spain) to $14 865 (Australia); those of ledipasvir-sofosbuvir from $12 604 (USA) to $24 890 (Germany); and those of the 2D regimen from $15 344 (UK) to $20 215 (Switzerland). In low-income and middle-income countries, prices were generally substantially lower than in highincome countries. However, there Disparity in market prices for hepatitis C virus direct-acting drugs

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New treatment of hepatitis C (Direct Acting Antiviral)

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with approximately 71 million chronically infected individuals worldwide. Clinical care for the patients with HCV-related liver disease has advanced considerably thanks to an enhanced understanding of the pathophysiology of the disease, and because of developments in diagnostic procedures and improvements in therapy an...

متن کامل

Detection of Pre-treatment mutations leading to resistance to direct hepatitis C virus blocking drugs in patients with chronic hepatitis C

Background and objective: Human is the only host of hepatitis C virus. This virus has a positive single stranded RNA and lipoprotein envelop that has 7 confirmed genotypes. According to studies, genotypes 1a, 3a and 1b are the most common genotypes in Iran. No effective vaccine against HCV infection has been developed instead, advances in antiviral treatment using drugs that directly affect spe...

متن کامل

Immunological Response and Prevalence of Occult HCV Genotype 4 Among Patients Receiving Direct-Acting Antiviral (DAA) Drugs: A Cross-sectional Study

Background and Objective: Infection with the hepatitis C virus (HCV) is an endemic public health problem with long-term consequences, especially in Egypt. Egypt has one of the highest incidence rates of HCV worldwide. The current cross-sectional study aims to determine how prevalent occult HCV infection is and how it affects the individual's immune response. Methods: The studied adult patient...

متن کامل

الگوهای جدید درمانی برای عفونت ویروس هپاتیت C

Hepatitis C virus (HCV) infection has affected approximately 180 million people across the world. In most cases, HCV-infection remains chronic, which expose patients at high risk of cirrhosis and hepatocellular carcinoma. The rates of disease incidence and mortality diminish as a result of successful treatment of HCV infection. Until the recent years, despite the associated toxicities and l...

متن کامل

Mechanisms of Hepatitis C Viral Resistance to Direct Acting Antivirals

There has been a remarkable transformation in the treatment of chronic hepatitis C in recent years with the development of direct acting antiviral agents targeting virus encoded proteins important for viral replication including NS3/4A, NS5A and NS5B. These agents have shown high sustained viral response (SVR) rates of more than 90% in phase 2 and phase 3 clinical trials; however, this is sligh...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Lancet. Global health

دوره 3 11  شماره 

صفحات  -

تاریخ انتشار 2015